A recent study published in NIH found that electronic nicotine delivery systems (ENDS) seem to cause less bronchial epithelial cells toxicity in comparison to cigarettes.
Titled, “Electronic nicotine delivery systems exhibit reduced bronchial epithelial cells toxicity compared to cigarette: the Replica Project,” the study aimed to replicate three published studies looking and comparing the cytotoxic and inflammatory effects of cigarette smoke and ENDS aerosol, in an independent multi-center ring study.
The research team established the reliability of results and the robustness of conclusions by replicating the authors’ experimental protocols and then also validating via different methods. After human bronchial epithelial cells (NCI-H292) were exposed to cigarette smoke and e-cig vapour, the researchers assessed the inflammatory cytokines interleukin-6 and interleukin-8 and the remodeling mediator matrix metalloproteinase-1.
Diane Caruana – VapingPost – 2022-07-15
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