Immortal time bias strikes again

Date:

I don’t write much about e-cigarette junk science because there is too much of it and it is just too depressing.

But I just came across this effort, which I missed earlier in the year, because I saw someone tweet about it. It’s worth looking at as a cautionary tale about statistics.

It’s the first study I’ve come across that purports to show that vaping gives you cancer. The headline claim is:

The e-cigarette users have lower prevalence of cancer compared to traditional smoking (2.3% vs. 16.8%; P < 0.0001), but they were diagnosed with cancer at a younger age.

Even the suggestion that vapers have a (much) lower rate of cancer than smokers seemed doubtful after they did a regression analysis…

Read full article here.

Christopher Snowdon – The Snowdon Substack – 2022-07-25

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