The paper is based on a false premise and should be extensively revised or withdrawn
The “EVALI” (E-cigarette, or Vaping, product use-Associated Lung Injury) outbreak of severe lung injuries in 2019 in the United States was not caused by nicotine e-cigarettes or any nicotine-based vaping product.
It was caused by cannabis (THC) vapes adulterated with Vitamin E Acetate and possibly other thickeners added as cutting agents by unscrupulous illicit vendors. Such thickeners cannot be added to nicotine e-liquids and would serve no useful purpose if they could.
I have set out the reasons why nicotine vaping cannot be implicated in EVALI in a pre-print [1]. I invite the authors to respond to this, explaining how they think nicotine vapes could somehow be implicated in EVALI and to consider revising or withdrawing their publication in the Annual Review of Physiology. I reproduce an extract from the abstract below:
Clive Bates – Pubpeer – 2022-02-10.